Bio-orgaaninen kemia (7.5 op / 5.0 ov) |
| Abbreviation: BOK |
| Learning outcomes: Knowledge of basics of Nucleic acids chemistry |
| Content: Being fundamental to molecular biology, nucleic acids chemistry has moved into biology and medicine.
The present course covers basics of nucleoside chemistry and chemistry of nucleic acids as well as
perspectives of application of these compounds as therapeutics. Synthetic and analytical techniques will
be taught in the practical laboratory work, where automated oligonucleotide synthesis will be performed
and the resulting products will be isolated by High Performance Liquid Chromatography and thoroughly
characterized. The aim of this work is to obtain basic skills for performing the syntheses of
oligonucleotides and modified oligonucleotides. The laboratory syntheses are connected to the on-going
research projects in the department. |
| Learning Material: Material distributed during lectures. Recommended literature:
S Hecht, ed., Bioorganic Chemistry: Nucleic Acids,
G.M Blackburn, M.J.Gait, eds., Nucleic Acids in Chemistry and Biology,
S Hecht, ed., Bioorganic Chemistry: Carbohydrates. |
| Degree / Programme: PR4, PR5, BB3, graduate students, Ph.D students |
| Teaching / Learning methods: Lectures 25 h, Tutorial 75 h, Independent Study 100 h |
| Teaching Languages: English |
| JOO-studies: JOO (flexible study right) students |
| Conduct: Written Examination, Practical Exercises |
| Assessment: 0 (Fail) - 5 (Excellent) |
| Organizing Department: Department of Pharmaceutical Chemistry |
| Course Director: Professor Alex Azhayev |
| Teachers: Professor Alex Azhayev |
| Contact Persons: Alex.Azhayev@uku.fi |
| Registration for the course: Wossikka in autumn term, WebOodi in spring term |